Nikon Small World

Klymkowsky’s image was captured as part of a research project to characterize the anti-Sox3 antibody. It shows the distribution of a protein (the transcription factor Sox3) in early clawed frog (Xenopus laevis) embryos. The Sox3 protein plays a key role in establishing the early regional divisions in the embryo. The protein acts to turn on the expression of some genes and turn off the expression of others, so the region in which it is expressed becomes ectodermal - and later goes on to form the skin and nervous system. Later in development Sox3 and related proteins controls neuronal proliferation and differentiation.

The image was created using a standard photomicroscope and a Nikon CoolPix 995 camera. The images were adjusted for color using Fireworks software on a Mac.

Complete information on all Nikon Instruments products and services.

Learn about optical microscopy, digital imaging, and photomicrography.

Nikon’s free online digital photo storage and sharing service.

From the nanoworld to the universe — the worlds we measure using our infinite yardstick.

Enjoy learning about Nikon’s long history through a series of interactive episodes.