2013 Small World In Motion Competition

Heart of a two day old zebrafish

Dr. Michael Weber

Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)
Dresden, Germany

Light Sheet Microscopy (Selective Plane Illumination Microscopy)


This video shows the beating heart of a two-day old zebrafish embryo. The heart – which is only 250 micrometers or just a bit more than the diameter of a human hair – was reconstructed in 3D after being captured using light sheet fluorescence microscopy in the living zebrafish. In one of its more mesmerizing facets, viewers can watch the movement of blood cells through the heart and its adjacent vessels.